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Western Medicine’s “Hail Mary”. Amazonian Entheogen Therapy for the treatment U.S. Military Veterans: Part Two. // Melanie Boling, Harvard University.

Western Medicine’s “Hail Mary”. Amazonian Entheogen Therapy for the treatment U.S. Military Veterans.

Western Medicine’s “Hail Mary”.

Ayahuasca is an entheogen that is a “rich source of serotonergic agonists and reuptake inhibitors” (de Araujo et al., 2012). Consuming the brew will provide a rapid increase in Occipital; Temporal; and Frontal areas of the brain. The experiences bring about changes in sensory perception and self-awareness. Visual imagery is internally generated without the need for additional stimuli. 

Ayahuasca affects brain areas responsible for psychopathological hallucinations and those activated during normal and rapid-eye-movement (REM) sleep. Studies have shown that cortical areas involved in memory retrieval and context increase in connectivity as a result of ingesting the substance (de Araujo et al., 2012). It is also responsible for the engagement of brain functions which allow the integration of memories and context to provide a whole scene of imagery to the user. “Seeing with the eyes shut” stems from the activation of several brain areas working together to produce “visions, memory, and intentions” (de Araujo et al., 2012).

Potential therapeutic uses for ayahuasca include disorders such as Addiction; Post-Traumatic Stress Disorder; Obsessive-Compulsive Disorder; and Regulation of Sleep are few and dependent on admixtures that can be used for a variety of treatment-resistant illnesses. Studies examined through the use of functional Magnetic Resonance Imaging (fMRI) have given a glimpse of the neural basis of this inner perception of the world (de Araujo et al., 2012). 

Terms such as hallucinogens; psychedelics; entheogens; or psychotomimetics have been problematic because of the societal connotations that stigmatize specific titles. Researchers must take into account the safeguards to be maintained for their subjects in order for human hallucinogen research to continue in the future. Hallucinogens are not deemed “drugs of dependence” (Johnson et al., 2008).  

The low physiological toxicity; absence of illicit drug-seeking behavior; and not contributing to any known withdrawal syndromes, make hallucinogens little risk for dependency among their users (Johnson et al., 2008). Factors to keep in mind are the psychological risks brought on by anxiety; paranoia; fear; dysphoria; and panic in humans and can potentially produce behaviors in subjects that could be a danger to themselves or others (Johnson et al., 2008).  

Guidelines for safety include

1. Selection of Volunteers.

2. Study Personnel.

3. Physical Environment.

4. Preparation of Volunteers.

5. Conduct of Hallucinogen Administration Sessions. 

6. Post-Session Procedures (Johnson et al., 2008). 

Trauma is individual to the person. With regard to the U.S. Military Veteran Community, mitigating potential risks would be an overall benefit to the researcher and user alike simply because no trauma is identical to the other, even within the same community.

Two veterans could go into the same battle and walk away with completely different experiences; thus, no approach to trauma and the application of plant medicine should be the same.

A personalized approach to each and every human subject must be emphasized and taking appropriate measures to safeguard human subjects will ensure the safety and well-being of research participants and allow scientific research of hallucinogens to continue.

(Artist Unknown, 2021).

(Artist Unknown, 2021).

Would you like to know more?

Be sure to read back on all of our articles about Entheogen Therapy or Psychedelic Plant Medicine derived from the scientific paper, “Reported results of Amazonian Entheogens for treatment of Complex-Post-Traumatic Stress Disorder (C-PTSD); Military Sexual Trauma (MST); and Traumatic Brain Injury (TBI) among U.S. Military Veterans and the benefits of application through small group indigenous shamanic ceremonies.


References:

Boling, Melanie (2021). Reported results of Amazonian Entheogens for treatment of Complex-Post-Traumatic Stress Disorder (C-PTSD); Military Sexual Trauma (MST); and Traumatic Brain Injury (TBI) among U.S. Military Veterans and the benefits of application through small group indigenous shamanic ceremonies. The Amazon Rainforest: From Conservation to Climate Change-research. Harvard Summer School, August 9, 2021.

A. Cecchi, Fabiana M. Carvalho, Tiago A. Sanchez, Joel P. Pinto, Bruno S. de Martinis, Jose A. Crippa, Jaime E.C. Hallak, and Antonio C. Santos. “Seeing with the Eyes Shut: Neural Basis of Enhanced Imagery Following Ayahuasca Ingestion.” Human Brain Mapping 33, no. 11 (November 2012): 2550–60. https://doi.org/10.1002/hbm.21381.


Johnson, Mw, Wa Richards, and Rr Griffiths. “Human Hallucinogen Research: Guidelines for Safety.” Journal of Psychopharmacology 22, no. 6 (August 2008): 603–20. https://doi.org/10.1177/0269881108093587.


About the author:

Melanie began attending Harvard in 2020 to complete a Graduate Certificate in Human Behavior with a specialization in Neuropsychology. Boling’s research has examined extreme environments and how they can have a potential negative impact on humans operating in the extreme environment. During her time at Harvard, she has built a mental wellness tool called a psychological field kit. Implementing these tools will allow an individual to thrive in an extreme environment while mitigating negative variables such as abnormal human behavior which can play a role in team degradation.

Melanie Boling, Extreme Environments Behavioural Ecologist and Graduate Student of Neuropsychology, Harvard University.

Melanie Boling, Extreme Environments Behavioural Ecologist and Graduate Student of Neuropsychology, Harvard University.

The Psychedelic Renaissance in 2021. // Melanie Boling, Harvard University.

The Psychedelic Renaissance in 2021.

“Ayahuasca, a hallucinogen brew prepared through the decoction of Banisteriopsis caapi stalks and Psychotria viridis leaves. Ayahuasca effects are caused by the interaction of β-carbolines contained in Banisteriopsis caapi stalks combined with the N,N-dimethyltryptamine (DMT) from Psychotria viridis leaves, a potent agonist to serotonin (5-HT) receptors. Benefits obtained from the brew intake, such as mind healing, increased self-knowledge, improved memory and persistently elevated mood”. It has gained recent traction with U.S. Military Veterans for seeking healing from treatment-resistant mental illness such as Anxiety, Obsessive-Compulsive Disorder and Depression.

“Ayahuasca, a hallucinogen brew prepared through the decoction of Banisteriopsis caapi stalks and Psychotria viridis leaves. Ayahuasca effects are caused by the interaction of β-carbolines contained in Banisteriopsis caapi stalks combined with the N,N-dimethyltryptamine (DMT) from Psychotria viridis leaves, a potent agonist to serotonin (5-HT) receptors. Benefits obtained from the brew intake, such as mind healing, increased self-knowledge, improved memory and persistently elevated mood”. It has gained recent traction with U.S. Military Veterans for seeking healing from treatment-resistant mental illness such as Anxiety, Obsessive-Compulsive Disorder and Depression.

Ayahuasca is gaining traction in our modern society after having remained in the shadows for decades.

The United States Government has deemed many plants as having no medicinal purpose within our country. As such, they were assigned as Schedule I drugs under the Controlled Substances Act making it illegal for possession, consumption, and research. This includes N-dimethyltryptamine or DMT, the active ingredient within ayahuasca.

With the proliferation of the internet and the ability to disseminate information at instantaneous speeds; coupled with the fact that most corners of the globe are now accessible by humans; entheogen research has pressed on, despite the legal hurdle that the United States Government has kept in place for over 50 years (The Controlled Substances Act, n.d.). As entheogen research gains more support globally, the opportunities to explore ayahuasca from a scientific perspective will grow.

Researchers, Healers, Shamans, Psychonauts, and those searching for a “hail mary”  (Londoño & Ferguson, 2020), in regards to treatment-resistant or incurable illnesses that cannot be solved by Western Medicine; many have found safety and solace in locations around the globe where entheogen consumption is in fact legal. Thus, finding alternative means for healthcare that provide the user a cure; or simply finding relief through a placebo effect granted facilitated by a shaman or similar practitioner of rainforest healing (Plotkin, 2021).

Today, the psychedelic renaissance is moving faster than its predecessor with the help of the internet and social media. Searching up keywords such as psychedelics, plant medicine, or even ayahuasca on a number of technological platforms will provide both valuable information and disinformation.

During the 1960s, the media controlled the narrative of psychedelics such as LSD labeling them as “drugs of dependence” (Johnson et al., 2008) that would make the user “crazy”, despite the United States Government testing these same substances on military forces.

The U.S. government deemed hallucinogens as having no medicinal value simply because they saw greater value in the investment and production of pharmaceuticals that would provide long-term profit, as well as means to control the population. 

50 years later, the scientific community is teaming up with a growing number of persons within our society to do away with the control that the government has held over substances like DMT, Psilocybin, and LSD for over half a century. I foresee that plant medicines like ayahuasca will in fact be legalized in the United States and available for research in laboratories around the country; and on the path for use by those who need it for medicinal use. 



Would you like to know more?

Be sure to read back on all of our articles about Entheogen Therapy or Psychedelic Plant Medicine derived from the scientific paper, “Reported results of Amazonian Entheogens for treatment of Complex-Post-Traumatic Stress Disorder (C-PTSD); Military Sexual Trauma (MST); and Traumatic Brain Injury (TBI) among U.S. Military Veterans and the benefits of application through small group indigenous shamanic ceremonies”.


References:

Boling, Melanie (2021). Reported results of Amazonian Entheogens for treatment of Complex-Post-Traumatic Stress Disorder (C-PTSD); Military Sexual Trauma (MST); and Traumatic Brain Injury (TBI) among U.S. Military Veterans and the benefits of application through small group indigenous shamanic ceremonies. The Amazon Rainforest: From Conservation to Climate Change-research. Harvard Summer School, August 9, 2021.

The Controlled Substances Act. (n.d.). Retrieved August 4, 2021, from https://www.dea.gov/drug-information/csa

Londoño, E., & Ferguson, A. (2020, August 30). ‘A Hail Mary’: Psychedelic Therapy Draws Veterans to Jungle Retreats. The New York Times. https://www.nytimes.com/2020/08/30/world/americas/psychedelics-therapy-war-stress.html

Plotkin, M. J. (2021). The Amazon: What everyone needs to know. lecture notes The Amazon Rainforest: From Conservation to Climate Change- seminar.  Harvard Summer School. Delivered July 2021.

Johnson, Mw, Wa Richards, and Rr Griffiths. “Human Hallucinogen Research: Guidelines for Safety.” Journal of Psychopharmacology 22, no. 6 (August 2008): 603–20. https://doi.org/10.1177/0269881108093587.


About the author:

Melanie began attending Harvard in 2020 to complete a Graduate Certificate in Human Behavior with a specialization in Neuropsychology. Boling’s research has examined extreme environments and how they can have a potential negative impact on humans operating in the extreme environment. During her time at Harvard, she has built a mental wellness tool called a psychological field kit. Implementing these tools will allow an individual to thrive in an extreme environment while mitigating negative variables such as abnormal human behavior which can play a role in team degradation.

Melanie Boling, Extreme (ICE) Environments Behavioural Ecologist, Peer Wild; and Graduate Student of Neuropsychology, Harvard University.

Melanie Boling, Extreme (ICE) Environments Behavioural Ecologist, Peer Wild; and Graduate Student of Neuropsychology, Harvard University.


contact: melanie.noelani@gopeerwild.org

contact: melanie.noelani@gopeerwild.org